Category: Research news

A blog from the research coal face

May 13, 2022

Jing Yu is a bioinformatician with the Eye Research Group at Oxford University, and is part of the UK Inherited Retinal Dystrophy Consortium (UKIRDC) team, funded by a Retina UK  …

Research update – ProQR

April 22, 2022

In February this year, ProQR announced a disappointing outcome for their phase 2/3 trial of sepofarsen for Leber congenital amaurosis type 10 (LCA10). These results prompted ProQR to undertake a …

Drugs for cancer and alcoholism show promise for RP

March 21, 2022

With all the interest in exciting gene and cell therapies for inherited sight loss, it’s easy to forget that more traditional drugs can also hold promise. Investigating the potential of …

Disappointing news from ProQR clinical trial for LCA10

February 15, 2022

ProQR has published the top-line results from its Phase 2/3 “Illuminate” trial of the RNA therapy sepofarsen for Leber congenital amaurosis type 10 caused by a specific mutation in the …

ReNeuron trial FAQs

February 9, 2022

UPDATE 14 February 2022 ReNeuron has announced that it is discontinuing the phase 2a clinical trial of its retinal progenitor cell therapy. This follows disappointing results due to surgical complications …

Beware of online adverts about treatments

December 16, 2021

The Retina UK community is sometimes targeted by adverts online or in social media, offering invasive treatments for inherited sight loss. Those selling the treatments are often outside of the …

Exciting developments for new treatment research

November 19, 2021

Update 6 January 2022 Towards the end of 2021, jCyte announced additional findings from the phase 2 trial that help to clarify the circumstances in which the treatment has the …

jCyte update

August 19, 2021

In spring 2021, the US company jCyte announced detailed results from their successful phase 2b clinical trial of jCell, a stem cell-based treatment for RP. What is jCell? jCell is …

Research brings hope for the future

June 25, 2021

“All the promising research makes you feel like there is light at the end of that very dark tunnel after all.” So said an attendee of Retina UK’s recent Annual …

Optogenetics

May 25, 2021

The BBC covered a story on Monday 24 May about optogenetics partially restoring the sight of a man living with retinitis pigmentosa in France. This is an area of research …

Study of substances in blood suggests choroideremia is not just an isolated eye disease

April 6, 2021

Choroideremia is a rare genetic condition resulting in progressive sight loss in men. Young boys suffer from difficulty with their night vision, followed by loss of their peripheral visual field …

Encouraging results from ProQR USH2A clinical trial

March 24, 2021

Biotechnology company ProQR has announced encouraging results from its phase 1/2 clinical trial of an innovative treatment for sight loss caused by faults in a specific section of the USH2A …