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Johnson & Johnson gene therapy update – What happens now?

The latest research news from Retina UK.

A machine with a digital display with a hand in a green glove pressing the screen with their index finger

Research grants

Retina UK aims not only to progress research along established threads, but to stimulate new thinking, encourage innovative approaches and nurture original ideas.

Breakthrough BBS10 treatment marks major milestone

Catherine L’Estrange, aged 11 from London has become the first individual in the UK to receive an investigative gene therapy treatment for retinal dystrophy associated with the BBS10 gene.

News

New mechanism of disease discovered for Retinitis Pigmentosa

The team have found the cause of disease in the first ever family tree drawn up at Moorfields Eye Hospital over 35 years ago, which had remained unsolved until now.

The cover of the Spring 2026 edition of Look Forward

Look Forward – Spring 2026 – Issue 189

Inside: Our intrepid Sahara Trek #TeamRetinaUK tell us about their incredible experience. 2026 is now fully underway and we are excited to tell you about our plans. Could you take part in a challenge event or volunteer to do a bucket collection in London for Retina UK?

Four people sitting in a line. The person furthest away from the camera is the only one facing towards it. He is wearing a white shirt

Involving our community

Our community is informed and knowledgeable about current research projects into the cause(s) of and treatments for these conditions.

Autoimmune Retinopathy

Autoimmune diseases are quite distinct from inherited retinal dystrophies.

Logos for the group of charities involved in the joint statement

Joint statement on benefits and employment support

As a coalition of sight loss charities, we are calling on the Government to make the benefit system and employment support fit for purpose for blind and partially sighted people.

News

A high power image showing the position of a single transplanted photoreceptor cell (green) making new connections with bipolar cells in the recipient retina (cyan).

Stem cells

Stem cells are a special type of cell, which under the right conditions can be encouraged to grow into any other type of cell in the body, including retinal cells (rods, cones and retinal pigment epithelial cells).

Sirius clinical trial – Exon 13 mutation of USH2A

Prof Mariya Moosajee at Moorfields Eye Hospital has asked us to share the message below about the clinical trial she is running. This trial is for a treatment that targets a particular section of the USH2A gene.