The following projects were being funded by Retina UK and have recently come to an end. Below is a brief summary of the outcomes of each project. If you would like more information, please contact our Research Development Manager, Kate Arkell on 01280 821334 or email kate.arkell@RetinaUK.org.uk
This project aims to explore the mutation of the RP2 gene, which is one cause of retinitis pigmentosa. The mechanism by which this happens is not fully understood, but current data suggests that a reduced ability to deal with oxidative stress and DNA damage may be the issue. This project will explore whether this is the underlying cause, and will also test whether drugs which target DNA repair pathways and/or antioxidant therapies represent a suitable treatment option.